SCHEMBL6322340

SCHEMBL6322340

CCCCCCCCCCC(O)COCc1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 3/20 0.53
RARB P10826 5/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
RARA P10276 1/20 0.50
MAPT P10636 1/20 0.50
MTOR P42345 1/20 0.50
KMT2A Q03164 1/20 0.50
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
PTGER4 P35408 3/20 0.47
PTGER2 P43116 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10798501 0.84 CA1 (0.57) TSHR
SCHEMBL30342950 0.84 CA1 (0.57) TSHR
SCHEMBL31287893 0.84 CA1 (0.57) TSHR
SCHEMBL10844759 0.84 CA1 (0.57) TSHR
SCHEMBL31362241 0.84 CA1 (0.57) TSHR
SCHEMBL9661280 0.84 CA1 (0.57) TSHR
SCHEMBL9662621 0.83 CA1 (0.58) KMT2ATSHR
SCHEMBL29127647 0.81 RARB (0.56) PLA2G4BRARBMEN1ALDH1A1RARA
SCHEMBL15153312 0.80 PLA2G4B (0.67) PLA2G4BRARBMEN1ALDH1A1RARA
SCHEMBL9321559 0.80 PLA2G4B (0.67) PLA2G4BRARBMEN1ALDH1A1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6884842-B2 Molecular compounds having complementary surfaces to targets ALNIS BIOSCIENCES, INC. (US) 2005-04-26 US disclosed
US-20030153001-A1 Molecular compounds having complementary surfaces to targets ALNIS, LLC 2003-08-14 US disclosed
EP-1025066-A2 MOLECULAR COMPOUNDS HAVING COMPLEMENTARY SURFACES TO TARGETS Alnis, LLC (US) 2000-08-09 EP disclosed
WO-1999019276-A2 MOLECULAR COMPOUNDS HAVING COMPLEMENTARY SURFACES TO TARGETS ALNIS, LLC (US) 1999-04-22 WO disclosed