Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18369760 | 0.74 | UHRF1 (0.82) | UHRF1KMT2AALDH1A1MEN1IGF1R | |
| SCHEMBL10286563 | 0.72 | UHRF1 (0.41) | UHRF1KMT2AALDH1A1MEN1GAA | |
| SCHEMBL4241202 | 0.70 | MEN1 (0.41) | UHRF1KMT2AALDH1A1MEN1GAA | |
| SCHEMBL6325164 | 0.69 | UHRF1 (1.00) | UHRF1KMT2AALDH1A1MEN1GAA | |
| SCHEMBL7916071 | 0.68 | TSHR (0.44) | UHRF1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL8067184 | 0.64 | UHRF1 (0.70) | UHRF1KMT2AALDH1A1MEN1GAA | |
| SCHEMBL31600787 | 0.64 | UHRF1 (0.56) | UHRF1KMT2AALDH1A1MEN1GAA | |
| SCHEMBL10286569 | 0.63 | MEN1 (0.35) | UHRF1KMT2AALDH1A1MEN1GAA | |
| SCHEMBL10286500 | 0.63 | MEN1 (0.49) | UHRF1KMT2AALDH1A1MEN1GAA | |
| SCHEMBL20416986 | 0.63 | UHRF1 (0.50) | UHRF1ALDH1A1GAAHPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004200-A1 | Pyrazole compounds as integrin receptor antagonists derivatives | PHARMACIA CORPORATION | 2005-01-06 | — | — | US | disclosed |
| WO-2004058761-A1 | PYRAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004200-A1 | Pyrazole compounds as integrin receptor antagonists derivatives | ITGA5, ITGB3, ITGB5 | UHRF1 4856/4885KMT2A 4015/4885ALDH1A1 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.