Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 9/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | CIT | O14578 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321238 | 0.90 | PIN1 (0.55) | PIN1OPRM1TAS1R3TAS1R1CIT | |
| SCHEMBL6326404 | 0.87 | PIN1 (0.59) | PIN1OPRM1TAS1R3TAS1R1CIT | |
| SCHEMBL6322839 | 0.79 | PIN1 (0.66) | PIN1OPRM1TAS1R3TAS1R1CIT | |
| SCHEMBL6325242 | 0.78 | PIN1 (0.76) | PIN1OPRM1TAS1R3TAS1R1CIT | |
| SCHEMBL6326648 | 0.75 | PIN1 (0.76) | PIN1OPRM1TAS1R3TAS1R1CIT | |
| SCHEMBL6326102 | 0.73 | PIN1 (0.57) | PIN1 | |
| SCHEMBL6269848 | 0.71 | PIN1 (0.79) | PIN1OPRM1TAS1R3TAS1R1CIT | |
| SCHEMBL16550476 | 0.71 | PIN1 (1.00) | PIN1OPRM1TAS1R3TAS1R1HDAC2 | |
| SCHEMBL16550475 | 0.71 | PIN1 (1.00) | PIN1OPRM1TAS1R3TAS1R1HDAC2 | |
| SCHEMBL6331037 | 0.71 | PIN1 (1.00) | PIN1OPRM1TAS1R3TAS1R1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PFIZER INC. | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PIN1, PSTPIP2, NIM1K | PIN1 1/4885OPRM1 3859/4885TAS1R3 4858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.