SCHEMBL6323102

SCHEMBL6323102

O=C(O)CN(CC(=O)O)C(O)CO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
OR51E2 Q9H255 1/20 0.38
EYA2 O00167 1/20 0.38
APP P05067 1/20 0.38
ACE P12821 1/20 0.38
TSHR P16473 2/20 0.36
BLM P54132 2/20 0.36
PMP22 Q01453 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
CHRM2 P08172 1/20 0.36
ADRA2A P08913 1/20 0.36
ALOX15 P16050 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
CYP2C19 P33261 1/20 0.36
ADRA1A P35348 1/20 0.36
DRD3 P35462 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3838592 0.77 FFAR3 (0.36) TDP1EYA2APPACETSHR
SCHEMBL78809 0.75 TDP1 (0.46) TDP1EYA2APPACETSHR
SCHEMBL20068572 0.73 GABRR1 (0.38) TDP1OR51E2EYA2APPACE
SCHEMBL28518317 0.73 TDP1 (0.44) TDP1EYA2APPACETSHR
SCHEMBL9487204 0.73 HDAC1 (0.41) TDP1EYA2APPACETSHR
SCHEMBL652071 0.72 TDP1 (0.36) TDP1OR51E2EYA2APPACE
SCHEMBL652072 0.72 TDP1 (0.36) TDP1OR51E2EYA2APPACE
SCHEMBL7927795 0.72 TDP1 (0.54) TDP1EYA2APPACETSHR
SCHEMBL124790 0.70 TDP1 (0.39) TDP1EYA2APPACETSHR
SCHEMBL731600 0.70 TDP1 (0.31) TDP1EYA2APPACETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100482282-C High water-soluble prodrug, and its preparing method and pharmaceutical use HONG ZHAO (CN) 2009-04-29 CN claimed
CN-1709516-A High water-soluble prodrug, and its preparing method and pharmaceutical use ZHAO HONG (CN) 2005-12-21 CN claimed
CN-100482282-C High water-soluble prodrug, and its preparing method and pharmaceutical use HONG ZHAO (CN) 2009-04-29 CN disclosed
CN-1709516-A High water-soluble prodrug, and its preparing method and pharmaceutical use ZHAO HONG (CN) 2005-12-21 CN disclosed
US-6881532-B2 Method of processing light sensitive planographic printing plate precursor and pre-washing solution used in the method KONICA CORPORATION (JP) 2005-04-19 US disclosed
US-20040072102-A1 Method of processing light sensitive planographic printing plate precursor and pre-washing solution used in the method KONICA CORPORATION (JP) 2004-04-15 US disclosed
EP-1388760-A1 Method of processing light sensitive planographic printing plate precursor KONICA CORPORATION (JP) 2004-02-11 EP disclosed