Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | EYA2 | O00167 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL2540798 | 0.81 | TDP1 (0.58) | TDP1EYA2APPACEBLM | |
| SCHEMBL78809 | 0.77 | TDP1 (0.46) | TDP1EYA2APPACEBLM | |
| SCHEMBL9342996 | 0.77 | TDP1 (0.52) | TDP1EYA2APPACEBLM | |
| SCHEMBL8768053 | 0.77 | TDP1 (0.52) | TDP1EYA2APPACEBLM | |
| SCHEMBL5949964 | 0.77 | TDP1 (0.52) | TDP1EYA2APPACEBLM | |
| SCHEMBL9487204 | 0.76 | HDAC1 (0.41) | TDP1EYA2APPACETSHR | |
| SCHEMBL28518317 | 0.76 | TDP1 (0.44) | TDP1EYA2APPACEBLM | |
| SCHEMBL20068572 | 0.76 | GABRR1 (0.38) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL8607480 | 0.72 | TDP1 (1.00) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL8624198 | 0.72 | TDP1 (1.00) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258286-A | Adding chelating agent; accurate analysis | ORIENTAL YEAST CO., LTD. (JP) | 1993-11-02 | — | — | US | claimed |
| US-9457312-B2 | Sequestration and release of carbon dioxide | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2016-10-04 | — | — | US | disclosed |
| US-20140371478-A1 | SEQUESTRATION AND RELEASE OF CARBON DIOXIDE | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2014-12-18 | — | — | US | disclosed |
| US-6235093-B1 | SOLUTIONS OF WATER AND NOBLE METALS FOR REDUCTION | DAIWA FINE CHEMICALS CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| US-5258286-A | Adding chelating agent; accurate analysis | ORIENTAL YEAST CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0476000-B1 | IMPROVED METHOD OF PHOTOGRAPHIC COLOR DEVELOPMENT | EASTMAN KODAK COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| US-4975357-A | Aminopolycarboxylic acid | EASTMAN KODAK COMPANY (US) | 1990-12-04 | — | — | US | disclosed |
| WO-1990014615-A1 | IMPROVED METHOD OF PHOTOGRAPHIC COLOR DEVELOPMENT | EASTMAN KODAK COMPANY (US) | 1990-11-29 | — | — | WO | disclosed |
| EP-0207493-B1 | METHOD OF TERMINATING ISOCITRATE DEHYDROGENASE REACTION | ORIENTAL YEAST CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| EP-0199363-B1 | METHOD OF TERMINATING ISOCITRATE DEHYDROGENASE REACTION | ORIENTAL YEAST CO., LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |
| US-4742001-A | NICOTINAMIDE ADENINE DINUCLEOTIDE | ORIENTAL YEAST CO. LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0207493-A2 | Method of terminating isocitrate dehydrogenase reaction | ORIENTAL YEAST CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |
| EP-0199363-A1 | Method of terminating isocitrate dehydrogenase reaction | ORIENTAL YEAST CO., LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371478-A1 | SEQUESTRATION AND RELEASE OF CARBON DIOXIDE | SCO2, CA2, CA7 | TDP1 3387/4885EYA2 4532/4885APP 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.