Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321391 | 0.91 | AGTR1 (0.50) | AGTR1AGTR2TP53POLB | |
| SCHEMBL6321104 | 0.89 | AGTR1 (0.49) | AGTR1AGTR2TP53POLB | |
| SCHEMBL6322945 | 0.88 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL6321473 | 0.88 | AGTR1 (0.41) | AGTR1AGTR2TP53 | |
| SCHEMBL6322287 | 0.87 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL6327652 | 0.87 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL6320084 | 0.87 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL6319209 | 0.86 | AGTR1 (0.46) | AGTR1AGTR2POLB | |
| SCHEMBL6327521 | 0.86 | HIF1A (0.49) | AGTR1AGTR2TP53 | |
| SCHEMBL6321807 | 0.86 | MEN1 (0.43) | AGTR1AGTR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906075-B2 | Melanin concentrating hormone receptor ligands: substituted benzoimidazole analogues | NEUROGEN CORP. (US) | 2005-06-14 | — | — | US | claimed |
| EP-1465888-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED BENZOIMIDAZOLE ANALOGUES | NEUROGEN CORPORATION (US) | 2004-10-13 | — | — | EP | claimed |
| WO-2003059289-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED BENZOIMIDAZOLE ANALOGUES | NEUROGEN CORPORATION (US) | 2003-07-24 | — | — | WO | claimed |
| US-6906075-B2 | Melanin concentrating hormone receptor ligands: substituted benzoimidazole analogues | NEUROGEN CORP. (US) | 2005-06-14 | — | — | US | disclosed |