SCHEMBL6323141

SCHEMBL6323141

C=C(C)C(=O)OCCc1cccc(-c2ccccc2C(=O)O)c1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 7/20 0.58
MAPK1 P28482 1/20 0.41
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MYC P01106 1/20 0.38
PTPN11 Q06124 1/20 0.38
THRB P10828 1/20 0.37
PPARG P37231 2/20 0.36
PPARA Q07869 2/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36344 0.90 POLB (0.43) FOLH1POLBAPEX1HTTTDP1
SCHEMBL21112016 0.85 FOLH1 (0.50) FOLH1POLBAPEX1HTTTDP1
SCHEMBL2597547 0.83 TSHR (0.47) FOLH1MAPK1POLBAPEX1HTT
SCHEMBL5442445 0.82 POLB (0.47) FOLH1POLBAPEX1HTTTDP1
SCHEMBL27459251 0.81 KMT2A (0.44) FOLH1POLBAPEX1HTTTDP1
Itaconate SCHEMBL2638844 0.81 HTT (0.37) FOLH1POLBAPEX1HTTTDP1
SCHEMBL5441216 0.81 POLB (0.49) FOLH1POLBAPEX1HTTTDP1
Phthalic Acid SCHEMBL4599263 0.81 TDP1 (0.51) FOLH1POLBAPEX1HTTTDP1
SCHEMBL11963930 0.81 HTT (0.42) FOLH1POLBAPEX1HTTTDP1
Phosphoric Acid SCHEMBL17294765 0.81 FOLH1 (0.45) FOLH1POLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050185232-A1 Volume hologram recording photosensitive composition and its use NIPPON PAINT CO., LTD. (JP) 2005-08-25 US disclosed