Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BID | P55957 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36344 | 0.91 | POLB (0.43) | HTTPOLBAPEX1TDP1FOLH1 | |
| SCHEMBL5442445 | 0.83 | POLB (0.47) | HTTPOLBAPEX1TDP1FOLH1 | |
| SCHEMBL5441216 | 0.82 | POLB (0.49) | HTTPOLBAPEX1TDP1FOLH1 | |
| SCHEMBL6323141 | 0.81 | FOLH1 (0.58) | HTTPOLBAPEX1TDP1FOLH1 | |
| SCHEMBL6231696 | 0.81 | POLB (0.34) | HTTPOLBAPEX1TDP1FOLH1 | |
| SCHEMBL9109022 | 0.81 | POLB (0.34) | HTTPOLBAPEX1TDP1FOLH1 | |
| SCHEMBL9109026 | 0.81 | POLB (0.34) | HTTPOLBAPEX1TDP1FOLH1 | |
| SCHEMBL21112016 | 0.79 | FOLH1 (0.50) | HTTPOLBAPEX1TDP1FOLH1 | |
| SCHEMBL19611833 | 0.79 | FOLH1 (0.40) | HTTPOLBAPEX1TDP1FOLH1 | |
| SCHEMBL28325652 | 0.78 | THRB (0.35) | HTTPOLBAPEX1TDP1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4791042-B2 | — | — | 2011-10-12 | — | — | JP | claimed |
| EP-1569512-B1 | PARTICULATE SUSPENSIONS | SYNGENTA LTD (GB) | 2007-02-28 | — | — | EP | claimed |
| US-20060116290-A1 | Particulate suspensions | SYNGENTA CROP PROTECTION, INC. | 2006-06-01 | — | — | US | claimed |
| EP-1569512-A2 | PARTICULATE SUSPENSIONS | Syngenta Limited (GB) | 2005-09-07 | — | — | EP | claimed |
| WO-2004052099-A2 | PARTICULATE SUSPENSIONS | SYNGENTA LIMITED (GB) | 2004-06-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116290-A1 | Particulate suspensions | PFAS, VCL, JMJD7 | HTT 1259/4885POLB 901/4885APEX1 1537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.