Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19152631 | 0.72 | ALDH1A1 (0.37) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL19153372 | 0.72 | KDM4E (0.38) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL7536489 | 0.70 | HTT (0.38) | XDHLMNATSHRADORA2ASLC6A4 | |
| SCHEMBL5964461 | 0.69 | PARP1 (0.53) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL7366251 | 0.69 | PARP1 (0.53) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL18238450 | 0.69 | HSD17B10 (0.33) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL18238040 | 0.69 | ALDH1A1 (0.33) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| Hydrochloric Acid SCHEMBL29539819 | 0.68 | PARP1 (0.52) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL14912053 | 0.67 | AURKA (0.41) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL19153720 | 0.67 | ALDH1A1 (0.43) | SLC2A1ALDH1A1PARP1PRKCIPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947729-A | Preparation method of intermediate of aldose reductase inhibitor | 成都新源康成医药科技有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-115947729-A | Preparation method of intermediate of aldose reductase inhibitor | 成都新源康成医药科技有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-115947729-A | Preparation method of intermediate of aldose reductase inhibitor | 成都新源康成医药科技有限公司 | 2023-04-11 | — | — | CN | disclosed |
| EP-1423120-A4 | 2H-PHTHALAZIN-1-ONES AND METHODS FOR USE THEREOF | ICOS CORP (US) | 2005-12-28 | — | — | EP | disclosed |
| US-6924284-B2 | PARP inhibitors | ICOS CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |
| EP-1423120-A1 | 2H-PHTHALAZIN-1-ONES AND METHODS FOR USE THEREOF | ICOS CORPORATION (US) | 2004-06-02 | — | — | EP | disclosed |
| US-20040087588-A1 | Parp inhibitors | ICOS CORPORATION | 2004-05-06 | — | — | US | disclosed |
| WO-2003015785-A1 | 2H-PHTHALAZIN-1-ONES AND METHODS FOR USE THEREOF | ICOS CORPORATION (US) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087588-A1 | Parp inhibitors | PARP1, PARP2, PARP11 | SLC2A1 2330/4885ALDH1A1 338/4885PARP1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.