SCHEMBL6323387

SCHEMBL6323387

Cc1ccc(C(=O)c2ccc(N)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.76
LMNA P02545 3/20 0.76
SRD5A2 P31213 2/20 0.64
ACHE P22303 1/20 0.62
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.52
MAPT P10636 2/20 0.52
GAA P10253 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAOA P21397 1/20 0.50
AKR1C3 P42330 1/20 0.48
PKM P14618 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25980381 1.00 ALDH1A1 (0.76) ALDH1A1LMNASRD5A2ACHECES2
SCHEMBL17296970 0.88 TEAD4 (0.70) ALDH1A1LMNASRD5A2ACHESMN1; SMN2
SCHEMBL15294828 0.88 TEAD4 (0.70) ALDH1A1LMNASRD5A2ACHESMN1; SMN2
SCHEMBL17297293 0.88 TEAD4 (0.70) ALDH1A1LMNASRD5A2ACHESMN1; SMN2
SCHEMBL9097535 0.87 CA12 (0.59) ALDH1A1LMNASRD5A2MAPTCA2
SCHEMBL62657 0.87 CA12 (0.59) ALDH1A1LMNASRD5A2MAPTCA2
SCHEMBL204877 0.87 CA12 (0.59) ALDH1A1LMNASRD5A2MAPTCA2
SCHEMBL52200 0.87 ALDH1A1 (1.00) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL822185 0.87 ALDH1A1 (1.00) ALDH1A1LMNASRD5A2CES2CES1
Hydrochloric Acid SCHEMBL8640288 0.85 CA12 (0.57) ALDH1A1LMNASRD5A2MAPTCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715595-B Synthesis method of 4-aminobenzophenone compound 台州学院 2025-04-18 CN disclosed
WO-2023226264-A1 HYPERBRANCHED POLYPHENYL AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 苏州大学 2023-11-30 WO disclosed
CN-116715595-A Synthesis method of 4-aminobenzophenone compound 台州学院 2023-09-08 CN disclosed
US-11656226-B2 Image generation for detection and related methods C2Sense, Inc. (US) 2023-05-23 US disclosed
US-20210120193-A1 IMAGE GENERATION FOR DETECTION AND RELATED METHODS C2Sense, Inc. (US) 2021-04-22 US disclosed
US-9242977-B2 Trk-inhibiting compound ONO PHARMACEUTICAL CO., LTD. (JP) 2016-01-26 US disclosed
CN-103224436-B The preparation method of the amino diaryl ketone compound of a kind of neighbour WENZHOU UNIVERSITY (CN) 2015-09-02 CN disclosed
US-20150111865-A1 Trk-INHIBITING COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2015-04-23 US disclosed
US-8673540-B2 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2014-03-18 US disclosed
CN-103224436-A Preparation method of o-amino diaryl ketone compound UNIV WENZHOU 2013-07-31 CN disclosed
US-4201707-A Methine dyestuffs containing a phenyl azo group BAYER AKTIENGESELLSCHAFT (DE) 1980-05-06 US disclosed
US-4156086-A INTERMEDIATES FOR AZO DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-05-22 US disclosed
US-4138570-A METHINE DYE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed
US-4136033-A DIAZO COUPLERS SANDOZ LTD. (CH) 1979-01-23 US disclosed
US-4038268-A DIAZOTIZATION, COUPLING BAYER AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed
US-4032532-A AZO DYES SANDOZ LTD. (CH) 1977-06-28 US disclosed
US-4026697-A HERBICIDES AMERICAN CYANAMID COMPANY (US) 1977-05-31 US disclosed
US-4006128-A CELLULOSE ACETATES, VINYL POLYMERS, POLYOLEFINS, POLYESTERS BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US disclosed
US-3988300-A FOR CONTROLLING BROADLEAF WEEDS AND GRASSES AMERICAN CYANAMID COMPANY (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150111865-A1 Trk-INHIBITING COMPOUND LTK, ROR1, TEC ALDH1A1 2591/4885LMNA 3367/4885SRD5A2 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.