Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15603041 | 0.92 | PIK3R1 (0.85) | PIK3CAPIK3R1 | |
| SCHEMBL634821 | 0.90 | PIK3R1 (1.00) | PIK3CAPIK3R1 | |
| SCHEMBL632141 | 0.89 | PIK3CA (1.00) | PIK3CAPIK3R1 | |
| SCHEMBL633212 | 0.89 | PIK3R1 (0.79) | PIK3CAPIK3R1 | |
| SCHEMBL633173 | 0.87 | PIK3R1 (1.00) | PIK3CAPIK3R1 | |
| SCHEMBL15603053 | 0.87 | PIK3R1 (0.83) | PIK3CAPIK3R1 | |
| SCHEMBL20458896 | 0.85 | PIK3R1 (0.80) | PIK3CAPIK3R1 | |
| SCHEMBL633032 | 0.82 | PIK3CA (1.00) | PIK3CAPIK3R1 | |
| SCHEMBL632562 | 0.81 | PIK3CA (1.00) | PIK3CAPIK3R1 | |
| SCHEMBL893488 | 0.78 | PIK3CA (1.00) | PIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419429-B1 | IMIDAZOPYRAZINES AS INHIBITORS OF PROTEIN KINASES | CT NAC INVESTIGACIONES ONCOLOGICAS CNIO (ES) | 2014-03-26 | — | — | EP | claimed |
| US-8778935-B2 | Imidazopyrazines for use as kinase inhibitors | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO) (ES) | 2014-07-15 | — | — | US | disclosed |
| WO-2012052745-A1 | COMBINATIONS OF PI3K INHIBITORS WITH A SECOND ANTI -TUMOR AGENT | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-04-26 | — | — | WO | disclosed |
| EP-2419429-A1 | IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS | Centro Nacional de Investigaciones Oncológicas (CNIO) (ES) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119264-A1 | IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCÓLOGICAS (CNIO) (ES) | 2010-10-21 | — | — | WO | disclosed |