SCHEMBL6323554

SCHEMBL6323554

C(=C/c1nc(/C=C/c2ccccc2)c(/C=C/c2ccccc2)nc1/C=C/c1ccccc1)\c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
KDM4E B2RXH2 5/20 0.54
ALDH1A1 P00352 5/20 0.54
HPGD P15428 3/20 0.54
MAOB P27338 2/20 0.52
GRM4 Q14833 6/20 0.52
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
RELA Q04206 1/20 0.50
NFE2L2 Q16236 1/20 0.50
CYP19A1 P11511 1/20 0.50
MAOA P21397 1/20 0.50
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
MAPT P10636 1/20 0.48
PKM P14618 2/20 0.48
GRM5 P41594 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6323560 1.00 MEN1 (0.54) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL10435572 0.87 KDM4E (0.58) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL9703466 0.87 KDM4E (0.58) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL9000376 0.85 CA1 (0.50) MEN1KMT2AKDM4EALDH1A1HPGD
(Z)-1,2-Diphenylethene SCHEMBL443 0.82 MAOB (0.73) MEN1KMT2AALDH1A1MAOBCYP11B1
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.82 MAOB (0.73) MEN1KMT2AALDH1A1MAOBCYP11B1
(Z)-1,2-Diphenylethene SCHEMBL21847984 0.82 MAOB (0.73) MEN1KMT2AALDH1A1MAOBCYP11B1
(Z)-1,2-Diphenylethene SCHEMBL22712863 0.82 MAOB (0.73) MEN1KMT2AALDH1A1MAOBCYP11B1
(Z)-1,2-Diphenylethene SCHEMBL347707 0.82 MAOB (0.73) MEN1KMT2AALDH1A1MAOBCYP11B1
(Z)-1,2-Diphenylethene SCHEMBL9134296 0.82 MAOB (0.73) MEN1KMT2AALDH1A1MAOBCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5178842-A None JP disclosed
US-6921589-B2 Electroluminescent elements TORAY INDUSTRIES, INC. (JP) 2005-07-26 US disclosed
US-20020160227-A1 Electroluminescent elements KOHAMA AKIRA (JP) 2002-10-31 US disclosed
EP-1000998-B1 Electroluminescent element and devices TORAY INDUSTRIES (JP) 2002-10-09 EP disclosed
EP-1000998-A1 Electroluminescent element and devices TORAY INDUSTRIES, INC. (JP) 2000-05-17 EP disclosed
EP-0516409-B1 Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same MITSUI TOATSU CHEMICALS (JP) 1996-09-11 EP disclosed
US-5416213-A Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1995-05-16 US disclosed
JP-H05178842-A TETRAVINYLPYRAZINE COMPOUND, ITS PRODUCTION AND ELECTRIC FIELD LUMINESCENT ELEMENT USING THE SAME MITSUI TOATSU CHEM INC 1993-07-20 JP disclosed
EP-0516409-A2 Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-12-02 EP disclosed