SCHEMBL9703466

SCHEMBL9703466

C(=Cc1nc2ccccc2nc1C=Cc1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.58
RAB9A P51151 7/20 0.58
NPC1 O15118 6/20 0.58
MAPT P10636 6/20 0.58
KMT2A Q03164 6/20 0.58
ALDH1A1 P00352 5/20 0.58
MEN1 O00255 5/20 0.58
HPGD P15428 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
LMNA P02545 2/20 0.54
POLB P06746 2/20 0.54
GAA P10253 1/20 0.54
MAPK1 P28482 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
PKM P14618 3/20 0.53
PDGFRB P09619 1/20 0.52
PDGFRA P16234 1/20 0.52
HSP90AA1 P07900 1/20 0.50
GRM4 Q14833 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10435572 1.00 KDM4E (0.58) KDM4ERAB9ANPC1MAPTKMT2A
SCHEMBL6323560 0.87 MEN1 (0.54) KDM4ERAB9ANPC1MAPTKMT2A
SCHEMBL6323554 0.87 MEN1 (0.54) KDM4ERAB9ANPC1MAPTKMT2A
SCHEMBL14027211 0.86 NPC1 (0.50) KDM4ERAB9ANPC1MAPTKMT2A
SCHEMBL28412041 0.86 KDM4E (0.52) KDM4ERAB9ANPC1MAPTKMT2A
SCHEMBL10435153 0.84 KDM4E (0.49) KDM4ERAB9ANPC1MAPTKMT2A
SCHEMBL10435152 0.84 KDM4E (0.49) KDM4ERAB9ANPC1MAPTKMT2A
SCHEMBL10938995 0.83 CYP19A1 (0.59) KDM4ERAB9ANPC1MAPTKMT2A
SCHEMBL10938991 0.83 CYP19A1 (0.59) KDM4ERAB9ANPC1MAPTKMT2A
SCHEMBL8219137 0.81 KDM4E (0.48) KDM4ERAB9ANPC1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0220589-B1 PHOTOPOLYMERISABLE COMPOUND AND REGISTRATION MATERIAL CONTAINING IT HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP disclosed
EP-0389236-A2 Photopolymerisable composition Horsell Plc (GB) 1990-09-26 EP disclosed
EP-0149802-B1 2,3-Bis(arylethényl)quinoxalines, process for their preparation and their use as photoconducting compounds HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-26 EP disclosed
US-4737445-A 2,3-DIHYDRO-1H-CYCLOPENTA(B)QUINOLINE HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-12 US disclosed
EP-0220589-A2 Photopolymerisable compound and registration material containing it HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-06 EP disclosed
EP-0149802-A2 2,3-Bis(arylethényl)quinoxalines, process for their preparation and their use as photoconducting compounds HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-31 EP disclosed