Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319495 | 0.90 | IDO1 (0.51) | IDO1KMT2ACA12CA1CA2 | |
| SCHEMBL6307102 | 0.86 | CA12 (0.52) | IDO1KMT2ACA12CA1CA2 | |
| SCHEMBL10936011 | 0.84 | IDO1 (0.55) | IDO1CA12CA1CA2CA9 | |
| SCHEMBL28355289 | 0.84 | IDO1 (0.67) | IDO1KMT2ACA12CA1CA2 | |
| SCHEMBL26963101 | 0.80 | IDO1 (0.65) | IDO1KMT2ACA12CA1CA2 | |
| SCHEMBL23878482 | 0.79 | IDO1 (0.62) | IDO1KMT2ACA12CA1CA2 | |
| SCHEMBL23878395 | 0.79 | IDO1 (0.62) | IDO1KMT2ACA12CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL23878421 | 0.79 | IDO1 (0.62) | IDO1KMT2ACA12CA1CA2 | |
| SCHEMBL20601197 | 0.79 | IDO1 (0.62) | IDO1KMT2ACA12CA1CA2 | |
| SCHEMBL21198807 | 0.79 | IDO1 (0.62) | IDO1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858568-B2 | Metal lubricants containing a bridge complex | MEC INTERNATIONAL CORPORATION (JP) | 2005-02-22 | — | — | US | claimed |
| US-20020123435-A1 | Metal lubricants containing a bridge complex | MEC INTERNATIONAL CORPORATION | 2002-09-05 | — | — | US | claimed |