SCHEMBL28355289

SCHEMBL28355289

S=C(NCCc1ccccc1)SCc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.67
NPC1 O15118 4/20 0.61
RAB9A P51151 4/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA9 Q16790 2/20 0.56
LMNA P02545 2/20 0.54
GAA P10253 1/20 0.54
TAAR1 Q96RJ0 1/20 0.54
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
ALDH1A1 P00352 2/20 0.49
ALOX12 P18054 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
MEN1 O00255 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10936011 0.86 IDO1 (0.55) IDO1NPC1RAB9ASMN1; SMN2CA12
SCHEMBL6323640 0.84 IDO1 (0.53) IDO1NPC1RAB9ASMN1; SMN2CA12
SCHEMBL11609705 0.84 IDO1 (0.56) IDO1NPC1RAB9ASMN1; SMN2CA12
SCHEMBL26963101 0.81 IDO1 (0.65) IDO1CA12CA1CA2CA9
SCHEMBL6319495 0.81 IDO1 (0.51) IDO1SMN1; SMN2CA12CA1CA2
SCHEMBL11607091 0.81 IDO1 (0.52) IDO1NPC1RAB9ASMN1; SMN2CA12
SCHEMBL7191501 0.80 IDO1 (0.59) IDO1NPC1RAB9ASMN1; SMN2CA12
SCHEMBL23878395 0.80 IDO1 (0.62) IDO1CA12CA1CA2CA9
Ammonia Solution, Strong SCHEMBL23878421 0.80 IDO1 (0.62) IDO1CA12CA1CA2CA9
SCHEMBL23878394 0.80 IDO1 (0.62) IDO1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110683975-B Synthesis method of dialkyl amino alkyl dithioformate 成都理工大学 2021-04-09 CN disclosed
CN-110683975-A Synthesis method of dialkyl amino alkyl dithioformate 成都理工大学 2020-01-14 CN disclosed