Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192176 | 0.89 | NOS2 (0.93) | NOS2 | |
| SCHEMBL5191362 | 0.86 | NOS2 (1.00) | NOS2 | |
| SCHEMBL6835443 | 0.83 | NOS2 (0.73) | NOS2 | |
| SCHEMBL6325631 | 0.83 | NOS2 (0.62) | NOS2 | |
| SCHEMBL5194425 | 0.83 | NOS2 (0.77) | NOS2 | |
| SCHEMBL5193583 | 0.82 | NOS2 (0.88) | NOS2 | |
| SCHEMBL5194100 | 0.81 | NOS2 (0.79) | NOS2 | |
| SCHEMBL5193922 | 0.81 | NOS2 (0.79) | NOS2 | |
| SCHEMBL5193576 | 0.79 | NOS2 (0.78) | NOS2 | |
| SCHEMBL5191656 | 0.79 | NOS2 (0.76) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864263-B2 | N-heterocyclic derivatives as NOS inhibitors | BERLEX LABORATORIES, INC. (US) | 2005-03-08 | — | — | US | disclosed |