Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.64 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.63 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.63 |
| ▸ | TUBB | P07437 | 4/20 | 0.63 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.63 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.63 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.63 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.63 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.63 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.63 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.63 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.63 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.63 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.63 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.63 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009804 | 0.93 | ABCG2 (0.63) | ABCG2ABCB1TNFRSF1AMEN1KMT2A | |
| SCHEMBL31266997 | 0.84 | TUBB1 (0.60) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17529419 | 0.82 | KMT2A (0.56) | ABCG2TNFRSF1AMEN1KMT2ACYP1A1 | |
| SCHEMBL5608404 | 0.80 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7175444 | 0.80 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5614582 | 0.80 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25209364 | 0.80 | ABCG2 (0.61) | ABCG2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL12687626 | 0.80 | ABCG2 (0.72) | ABCG2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6456490 | 0.79 | TUBB4A (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12687508 | 0.79 | PDE4A (0.71) | ABCG2TUBB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887904-B2 | Substituted arylcycloalkanes, compositions containing them and use thereof | AVENTIS PHARMA S. A. (FR) | 2005-05-03 | — | — | US | disclosed |
| US-20030149072-A1 | Substituted arylcycloalkanes, compositions containing them and use thereof | AVENTIS PHARMA S.A. (FR) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149072-A1 | Substituted arylcycloalkanes, compositions containing them and use thereof | ABL1, MCL1, AHR | ABCG2 270/4885TUBB1 1801/4885TUBB4A 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.