Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL4465090 | 1.00 | TDP1 (0.75) | TDP1LMNAALOX15BLMPMP22 | |
| Phosphoric Acid SCHEMBL27751704 | 0.92 | TDP1 (0.63) | TDP1LMNAALOX15BLMPMP22 | |
| Phosphoramidic Acid SCHEMBL31749051 | 0.91 | TDP1 (0.71) | TDP1LMNAALOX15BLMPMP22 | |
| Methyl Phosphonate SCHEMBL6608618 | 0.91 | TDP1 (0.71) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL14870 | 0.87 | — | — | |
| SCHEMBL2128293 | 0.87 | TDP1 (1.00) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL5708652 | 0.87 | TDP1 (1.00) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL4185647 | 0.84 | TDP1 (0.60) | TDP1LMNAALOX15BLMPMP22 | |
| Methyl Alcohol SCHEMBL8853832 | 0.83 | — | — | |
| SCHEMBL4561634 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001641-A | Polymethacrylimide acid polymer and preparation and the method used | 陶氏环球技术有限责任公司 | 2017-08-01 | — | — | CN | claimed |
| US-20100041790-A1 | SELF-ETCHING DENTAL MATERIALS BASED ON (METH)ACRYLAMIDE PHOSPHATES | IVOCLAR VIVADENT AG (LI) | 2010-02-18 | — | — | US | claimed |
| US-7622538-B2 | Polymerizable dental material, characterized in that it contains at least one (meth)acrylamide phosphate; adhesives, coating materials and composites for dental purposes; hydrolysis-stable | IVOCLAR VIVADENT AG (LI) | 2009-11-24 | — | — | US | claimed |
| EP-1674066-B1 | Self-etching dental materials based on (meth)acrylamidophosphates | IVOCLAR VIVADENT AG (LI) | 2008-08-13 | — | — | EP | claimed |
| US-20060135719-A1 | Self-etching dental materials based on (METH) acrylamide phosphates | IVOCLAR VIVADENT AG (LI) | 2006-06-22 | — | — | US | claimed |
| EP-4094748-B1 | DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH OLIGOMERIC CUMOLHYDROPEROXIDE DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2023-09-20 | — | — | EP | disclosed |
| EP-4039220-B1 | DENTAL MATERIALS ON THE BASIS OF POLYMERISABLE THIOUREA DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2022-12-28 | — | — | EP | disclosed |
| EP-3692975-B1 | DENTAL MATERIALS WITH IMPROVED SETTING | IVOCLAR VIVADENT AG (LI) | 2022-05-18 | — | — | EP | disclosed |
| EP-3692976-B1 | DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH LOW ODOR CUMENE HYDROPEROXIDE DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2021-03-31 | — | — | EP | disclosed |
| EP-3692974-A1 | DENTAL MATERIALS WITH IMPROVED MECHANICAL CHARACTERISTICS | Ivoclar Vivadent AG (LI) | 2020-08-12 | — | — | EP | disclosed |
| EP-3692975-A1 | DENTAL MATERIALS WITH IMPROVED SETTING | Ivoclar Vivadent AG (LI) | 2020-08-12 | — | — | EP | disclosed |
| EP-3692976-A1 | DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH LOW ODOR CUMOLHYDE-HYDROPEROXIDE DERIVATIVES | Ivoclar Vivadent AG (LI) | 2020-08-12 | — | — | EP | disclosed |
| US-7622538-B2 | Polymerizable dental material, characterized in that it contains at least one (meth)acrylamide phosphate; adhesives, coating materials and composites for dental purposes; hydrolysis-stable | IVOCLAR VIVADENT AG (LI) | 2009-11-24 | — | — | US | disclosed |
| EP-2103296-A1 | Polymer-coated glass filler for use in dental material | Ivoclar Vivadent AG (LI) | 2009-09-23 | — | — | EP | disclosed |
| EP-2065363-A1 | Dental materials based on alkylenediamine-N,N,N',N'-tetraacetic acid-(meth)acrylamides | Ivoclar Vivadent AG (LI) | 2009-06-03 | — | — | EP | disclosed |
| CN-1997690-A | Anisotropic shaped bodies, method for the production and utilization of anisotropic shaped bodies | PEMEAS GMBH (DE) | 2007-07-11 | — | — | CN | disclosed |
| JP-2006176522-A | (METH)ACRYLAMIDEPHOSPHATE-BASED SELF-ETCHING DENTAL MATERIAL | IVOCLAR VIVADENT AG | 2006-07-06 | — | — | JP | disclosed |
| EP-1674066-A1 | Self-etching dental materials based on (meth)acrylamidophosphates | Ivoclar Vivadent AG (LI) | 2006-06-28 | — | — | EP | disclosed |
| US-20060135719-A1 | Self-etching dental materials based on (METH) acrylamide phosphates | IVOCLAR VIVADENT AG (LI) | 2006-06-22 | — | — | US | disclosed |
| US-20060135719-A1 | Self-etching dental materials based on (METH) acrylamide phosphates | IVOCLAR VIVADENT AG (LI) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041790-A1 | SELF-ETCHING DENTAL MATERIALS BASED ON (METH)ACRYLAMIDE PHOSPHATES | MSR1, C1R, HRH3 | TDP1 3866/4885LMNA 720/4885ALOX15 1092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.