SCHEMBL6324504

SCHEMBL6324504

COS(=O)(=O)c1cc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)cc(S(=O)(=O)OC)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.62
CA12 O43570 3/20 0.59
CA9 Q16790 3/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA4 P22748 2/20 0.59
CA6 P23280 2/20 0.59
CA5A P35218 2/20 0.59
CA7 P43166 2/20 0.59
CA13 Q8N1Q1 2/20 0.59
CA14 Q9ULX7 2/20 0.59
TP53 P04637 1/20 0.59
KMT2A Q03164 3/20 0.59
MEN1 O00255 2/20 0.59
USP2 O75604 1/20 0.57
PPARG P37231 1/20 0.56
RAB9A P51151 1/20 0.56
RXFP1 Q9HBX9 1/20 0.56
NR2E3 Q9Y5X4 1/20 0.56
NCOR2 Q9Y618 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324634 0.89 CA12 (0.70) LMNACA12CA9CA1CA2
SCHEMBL6324950 0.88 LMNA (0.65) LMNACA12CA9CA1CA2
SCHEMBL6323942 0.83 KMT2A (0.62) LMNACA12CA9CA1CA2
SCHEMBL8416917 0.83 LMNA (0.72) LMNACA12CA9CA1CA2
SCHEMBL6243996 0.81 CA12 (0.85) LMNACA12CA9CA1CA2
SCHEMBL1928662 0.81 CA12 (0.85) LMNACA12CA9CA1CA2
SCHEMBL8416312 0.79 KMT2A (0.74) LMNACA12CA9CA1CA2
SCHEMBL8415602 0.79 LMNA (0.67) LMNACA12CA9CA1CA2
SCHEMBL6241750 0.79 LMNA (0.80) LMNACA12CA9CA1CA2
SCHEMBL6330120 0.78 LMNA (0.58) LMNACA12CA9CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed