⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988350 | 0.85 | — | — | |
| SCHEMBL10988354 | 0.85 | — | — | |
| SCHEMBL9286912 | 0.84 | — | — | |
| SCHEMBL2936108 | 0.80 | — | — | |
| SCHEMBL10988824 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL10988826 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL10988819 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL10896545 | 0.78 | CA1 (0.30) | — | |
| SCHEMBL10896539 | 0.78 | CA1 (0.30) | — | |
| SCHEMBL282623 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4366782-A1 | CONJUGATES OF CHECKPOINT INHIBITORS WITH IL-2, AND USES THEREOF | Bright Peak Therapeutics AG (CH) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023135398-A1 | ANTIBODY-DRUG CONJUGATES FOR THERAPEUTIC USE | MC SAF (FR) | 2023-07-20 | — | — | WO | disclosed |
| WO-2023281480-A1 | CONJUGATES OF CHECKPOINT INHIBITORS WITH IL-2, AND USES THEREOF | BRIGHT PEAK THERAPEUTICS AG (CH) | 2023-01-12 | — | — | WO | disclosed |
| EP-4087865-A2 | MODIFIED IL-2 POLYPEPTIDES AND USES THEREOF | Bright Peak Therapeutics AG (CH) | 2022-11-16 | — | — | EP | disclosed |
| US-6872792-B2 | Metathesis polymerization adhesives and coatings | LORD CORPORATION (US) | 2005-03-29 | — | — | US | disclosed |
| US-6800170-B2 | INCREASING THE BONDING STRENGTH TO SUBSTRATE, BY USING A POLYMERIZABLE MONOMER SELECTING FROM CYCLOBUTENE, NORBORNENE, AND A METALLIC COMPLEXES CATALYST TO FORM METATHESIS RING OPENING POLYMERIZATION | LORD CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-20030230598-A1 | Metathesis polymerization adhesives and coatings | LORD CORPORATION | 2003-12-18 | — | — | US | disclosed |
| US-20030058812-A1 | Metathesis polymerization adhesives and coatings | LORD CORPORATION | 2003-03-27 | — | — | US | disclosed |
| WO-2003000764-A2 | METATHESIS POLYMERIZATION ADHESIVES AND COATINGS | LORD CORPORATION (US) | 2003-01-03 | — | — | WO | disclosed |