SCHEMBL6324516

SCHEMBL6324516

CCCCCCCCOC(=O)c1cccc(NC(=O)NS(=O)(=O)c2cccc(C)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 9/20 0.54
SMN1; SMN2 Q16637 3/20 0.53
HPGD P15428 2/20 0.53
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PPARA Q07869 1/20 0.47
GPR35 Q9HC97 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
NLRP3 Q96P20 1/20 0.46
LMNA P02545 1/20 0.46
KCNA1 Q09470 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6331017 1.00 FBP1 (0.54) FBP1SMN1; SMN2HPGDRAB9ANPC1
SCHEMBL6321812 1.00 FBP1 (0.54) FBP1SMN1; SMN2HPGDRAB9ANPC1
SCHEMBL6325357 0.96 SMN1; SMN2 (0.58) FBP1SMN1; SMN2HPGDRAB9ANPC1
SCHEMBL1928907 0.96 FBP1 (0.55) FBP1SMN1; SMN2HPGDRAB9ANPC1
SCHEMBL1930100 0.96 FBP1 (0.55) FBP1SMN1; SMN2HPGDRAB9ANPC1
SCHEMBL1928977 0.96 FBP1 (0.55) FBP1SMN1; SMN2HPGDRAB9ANPC1
SCHEMBL1929818 0.96 FBP1 (0.55) FBP1SMN1; SMN2HPGDRAB9ANPC1
SCHEMBL1930806 0.96 FBP1 (0.55) FBP1SMN1; SMN2HPGDRAB9ANPC1
SCHEMBL1931132 0.95 FBP1 (0.54) FBP1SMN1; SMN2HPGDRAB9ANPC1
SCHEMBL1929181 0.93 FBP1 (0.54) FBP1SMN1; SMN2HPGDRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
EP-1501830-A1 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES Actelion Pharmaceuticals Ltd. (CH) 2005-02-02 EP disclosed
WO-2003093267-A1 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES ACTELION PHARMACEUTICALS LTD (CH) 2003-11-13 WO disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed