Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 10/20 | 0.73 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323785 | 0.86 | PIN1 (0.77) | PIN1CTSLLPAR1LPAR3CTRB1 | |
| SCHEMBL6326006 | 0.85 | PIN1 (1.00) | PIN1CTSLLPAR1LPAR3CTRB1 | |
| SCHEMBL6329760 | 0.85 | PIN1 (1.00) | PIN1CTSLLPAR1LPAR3 | |
| SCHEMBL6326344 | 0.85 | PIN1 (1.00) | PIN1CTSLLPAR1LPAR3 | |
| SCHEMBL6273717 | 0.82 | PIN1 (0.85) | PIN1CTSLLPAR1LPAR3 | |
| SCHEMBL6332073 | 0.80 | PIN1 (0.82) | PIN1LPAR1LPAR3 | |
| SCHEMBL6325255 | 0.78 | PIN1 (0.64) | PIN1CTSLLPAR1LPAR3 | |
| SCHEMBL6269412 | 0.77 | PIN1 (0.75) | PIN1LPAR1LPAR3CTRB1 | |
| SCHEMBL13754495 | 0.76 | NPC1 (0.64) | KMO | |
| SCHEMBL6269703 | 0.76 | PIN1 (0.72) | PIN1CTSLLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PFIZER INC. | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PIN1, PSTPIP2, NIM1K | PIN1 1/4885CTSL 3952/4885KMO 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.