Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL8400645 | 1.00 | CA5A (0.67) | CA5ACA5BALDH1A1TDP1TSHR | |
| Nitric Acid SCHEMBL2955802 | 1.00 | — | — | |
| Nitric Acid SCHEMBL417313 | 1.00 | CA5A (0.67) | CA5ACA5BALDH1A1TDP1TSHR | |
| Nitric Acid SCHEMBL27658815 | 0.96 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1TSHR | |
| Nitric Acid SCHEMBL28211265 | 0.96 | — | — | |
| Nitric Acid SCHEMBL3863157 | 0.96 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1TSHR | |
| Nitric Acid SCHEMBL28203691 | 0.96 | — | — | |
| Nitric Acid SCHEMBL28168626 | 0.96 | — | — | |
| Nitric Acid SCHEMBL27736484 | 0.96 | — | — | |
| Nitric Acid SCHEMBL9177805 | 0.89 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160052836-A1 | NON-PHTHALATE PROPELLANTS | BAE SYSTEMS PLC (GB) | 2016-02-25 | — | — | US | claimed |
| US-11802099-B2 | Or relating to energetic materials | LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) | 2023-10-31 | — | — | US | disclosed |
| US-20210371354-A1 | POLYMERISABLE BINDER | BAE SYSTEMS PLC (GB) | 2021-12-02 | — | — | US | disclosed |
| EP-3860965-A1 | POLYMERISABLE BINDER | BAE SYSTEMS plc (GB) | 2021-08-11 | — | — | EP | disclosed |
| EP-3838877-A1 | INSENSITIVE MUNITION PROPELLANTS | BAE SYSTEMS plc (GB) | 2021-06-23 | — | — | EP | disclosed |
| EP-2978730-B1 | INSENSITIVE MUNITION PROPELLANTS | BAE SYSTEMS PLC (GB) | 2021-05-05 | — | — | EP | disclosed |
| US-20200148609-A1 | IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS | LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) | 2020-05-14 | — | — | US | disclosed |
| WO-2020070472-A1 | POLYMERISABLE BINDER | BAE SYSTEMS PLC (GB) | 2020-04-09 | — | — | WO | disclosed |
| EP-3609858-A1 | IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS | Lewtas Science & Technologies Ltd (GB) | 2020-02-19 | — | — | EP | disclosed |
| US-20180305270-A1 | IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS | LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) | 2018-10-25 | — | — | US | disclosed |
| US-8864923-B1 | Ballistic modifier formulation for double base propellant | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-10-21 | — | — | US | disclosed |
| WO-2014155061-A1 | NON-PHTHALATE PROPELLANTS | BAE SYSTEMS PLC (GB) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014155060-A1 | INSENSITIVE MUNITION PROPELLANTS | BAE SYSTEMS PLC (GB) | 2014-10-02 | — | — | WO | disclosed |
| EP-2784053-A1 | Non- phthalate propellants | BAE SYSTEMS plc (GB) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784054-A1 | Insensitive munition propellants | BAE SYSTEMS plc (GB) | 2014-10-01 | — | — | EP | disclosed |
| US-8828161-B1 | Ballistic modification and solventless double base propellant, and process thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-09-09 | — | — | US | disclosed |
| US-6932878-B1 | Moldable; particulate explosive filler contained in a gelled binder which is a blend of a polyethylene wax and a polyisobutylene tackifying resin; reduced brittleness with ageing, low temperature moldability; hydrophobic for underwater use | BAE SYSTEMS PLC (GB) | 2005-08-23 | — | — | US | disclosed |
| US-6833037-B1 | Thermoplastic resin, high energy filler, and polymeric binder blend comprising ethylene-vinyl acetate copolymer and acrylonitrile-butadiene copolymer; gun and rocket propellants | BAE SYSTEMS PLC (GB) | 2004-12-21 | — | — | US | disclosed |
| US-5500060-A | IMPROVED SAFETY RELATED TO UNWANTED IGNITION, NITRAMINE COMPOUNDS, AROMATIC NITRO COMPOUNDS | ROYAL ORDNANCE PLC (GB) | 1996-03-19 | — | — | US | disclosed |
| US-4125445-A | WASTE WATER TREATMENT | HERCULES INCORPORATED (US) | 1978-11-14 | — | — | US | disclosed |