SCHEMBL6325257

SCHEMBL6325257

CCCCCCCCCCC[Si](C)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.42
LMNA P02545 3/20 0.42
EPHX1 P07099 1/20 0.37
DNM1 Q05193 6/20 0.33
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC22A1 O15245 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995736 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL114102 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL4806782 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL114288 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL16834820 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL143380 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL5841839 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL5843416 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL114514 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL1584714 1.00 TSHR (0.42) TSHRTHRBLMNAEPHX1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11033507-B2 Method of synthesis of silica vesicles and use thereof THE UNIVERSITY OF QUEENSLAND (AU) 2021-06-15 US disclosed
US-20180193278-A1 METHOD OF SYNTHESIS OF SILICA VESICLES AND USE THEREOF THE UNIVERSITY OF QUEENSLAND (AU) 2018-07-12 US disclosed
CN-105980447-A Method of synthesis of silica vesicles and use thereof 昆士兰大学 2016-09-28 CN disclosed
US-20050118742-A1 Method for reducing the adhesive properties of MEMS and anti-adhesion-coated device ROBERT BOSCH GMBH (DE) 2005-06-02 US disclosed
US-6007927-A FOR PREVENTING UNDESIRABLE DETERIORATION OF DIELECTRIC PROPERTIES AND SHORTENING OF DURABILITY INDUCED BY THE IMPURITY IONS PRESENT IN POWDERY BARIUM TITANATE SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1999-12-28 US disclosed
US-5777038-A FLUOROPOLYMER; ELECTROLUMINESCENCE SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1998-07-07 US disclosed