SCHEMBL6325302

SCHEMBL6325302

CO[Si](OC)(OC)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.42
KCNN4 O15554 5/20 0.40
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 1/20 0.39
CES1 P23141 1/20 0.36
TSHR P16473 2/20 0.36
CA4 P22748 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
ESR1 P03372 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20658081 0.82 MAPK1 (0.44) MAPK1KCNN4ALDH1A1ALOX15CES1
SCHEMBL5428022 0.80 MAPK1 (0.42) MAPK1KCNN4ALDH1A1ALOX15CES1
SCHEMBL28405535 0.80 MAPK1 (0.48) MAPK1KCNN4ALDH1A1ALOX15CES1
SCHEMBL9171059 0.78 MAPK1 (0.46) MAPK1KCNN4ALDH1A1ALOX15CES1
SCHEMBL6512441 0.78 MAPK1 (0.46) MAPK1KCNN4ALDH1A1ALOX15CES1
SCHEMBL6323711 0.78 MAPK1 (0.41) MAPK1KCNN4ALDH1A1ALOX15CES1
SCHEMBL6332001 0.75 KCNN4 (0.39) MAPK1KCNN4ALDH1A1ALOX15TAAR1
SCHEMBL3202150 0.72 MAPK1 (0.40) MAPK1KCNN4ALDH1A1ALOX15TSHR
SCHEMBL27769942 0.70 MAPK1 (0.39) MAPK1KCNN4ALDH1A1ALOX15TAAR1
SCHEMBL27891666 0.70 KCNN4 (0.46) MAPK1KCNN4ALDH1A1ALOX15CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473684-B Process for producing siloxane polymer 东丽精细化工株式会社 2023-05-12 CN disclosed
US-10647821-B2 Production process for silicone polymer TORAY FINE CHEMICALS CO., LTD. (JP) 2020-05-12 US disclosed
US-20190023848-A1 PRODUCTION PROCESS FOR SILICONE POLYMER TORAY FINE CHEMICALS CO., LTD. (JP) 2019-01-24 US disclosed
CN-108473684-A The manufacturing method of siloxane polymer 东丽精细化工株式会社 2018-08-31 CN disclosed
US-20050118742-A1 Method for reducing the adhesive properties of MEMS and anti-adhesion-coated device ROBERT BOSCH GMBH (DE) 2005-06-02 US disclosed