SCHEMBL6512441

SCHEMBL6512441

CO[Si](OC)(OC)C(C)(c1ccccc1)[Si](OC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 3/20 0.43
ALOX15 P16050 1/20 0.43
KCNN4 O15554 4/20 0.39
TAAR1 Q96RJ0 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28405535 0.83 MAPK1 (0.48) MAPK1ALDH1A1ALOX15KCNN4TAAR1
SCHEMBL9171059 0.81 MAPK1 (0.46) MAPK1ALDH1A1ALOX15KCNN4TAAR1
SCHEMBL5428022 0.78 MAPK1 (0.42) MAPK1ALDH1A1ALOX15KCNN4TAAR1
SCHEMBL6325302 0.78 MAPK1 (0.42) MAPK1ALDH1A1ALOX15KCNN4TAAR1
SCHEMBL6512003 0.76 MAPK1 (0.41) MAPK1ALDH1A1ALOX15KCNN4TAAR1
SCHEMBL3202150 0.74 MAPK1 (0.40) MAPK1ALDH1A1ALOX15KCNN4TAAR1
SCHEMBL7638116 0.73 MAPK1 (0.48) MAPK1ALDH1A1ALOX15KCNN4TAAR1
SCHEMBL27891666 0.73 KCNN4 (0.46) MAPK1ALDH1A1ALOX15KCNN4HDAC3
SCHEMBL27769942 0.73 MAPK1 (0.39) MAPK1ALDH1A1ALOX15KCNN4TAAR1
SCHEMBL20658081 0.70 MAPK1 (0.44) MAPK1ALDH1A1ALOX15KCNN4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005100426-A1 A NANOPARTICLE OF CORE-SHELL TYPE, A METHOD FOR PREPARING THE SAME, A METHOD FOR PREPARING A LOW DIELECTRIC INSULATION FILM BY USING THE SAME, AND A LOW DIELECTRIC INSULATION FILM PREPARED THEREFROM POSTECH FOUNDATION (KR) 2005-10-27 WO claimed
US-9284456-B2 Superficially porous metal oxide particles, methods for making them, and separation devices using them AGILENT TECHNOLOGIES, INC. (US) 2016-03-15 US disclosed
US-9136244-B2 Semiconductor package having a metal member and a resin mold, which are bonded to a silane coupling agent and an intermediate layer of an oxide film HITACHI, LTD. (JP) 2015-09-15 US disclosed
US-20130161807-A1 METHOD FOR JOINTING METAL MEMBER AND RESIN AND JOINTED BODY THEREOF HITACHI, LTD. (JP) 2013-06-27 US disclosed
US-20130004772-A1 SUPERFICIALLY POROUS METAL OXIDE PARTICLES, METHODS FOR MAKING THEM, AND SEPARATION DEVICES USING THEM AGILENT TECHNOLOGIES, INC. (US) 2013-01-03 US disclosed
US-20120205010-A1 CORROSION CONTROL METHOD OF METAL HITACHI, LTD. 2012-08-16 US disclosed
WO-2005100426-A1 A NANOPARTICLE OF CORE-SHELL TYPE, A METHOD FOR PREPARING THE SAME, A METHOD FOR PREPARING A LOW DIELECTRIC INSULATION FILM BY USING THE SAME, AND A LOW DIELECTRIC INSULATION FILM PREPARED THEREFROM POSTECH FOUNDATION (KR) 2005-10-27 WO disclosed