Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29573828 | 0.89 | — | — | |
| SCHEMBL15059320 | 0.89 | — | — | |
| SCHEMBL3440828 | 0.89 | ALDH1A1 (0.56) | CA2CA1TSHRALDH1A1ALOX15 | |
| SCHEMBL49313 | 0.89 | — | — | |
| SCHEMBL10560599 | 0.86 | — | — | |
| SCHEMBL38651119 | 0.86 | — | — | |
| SCHEMBL28504673 | 0.86 | — | — | |
| SCHEMBL31103367 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL21820164 | 0.86 | — | — | |
| SCHEMBL28504670 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441011-B1 | Energy transfer dye containing an aromatic-substituted xanthene dye as donor dye and/or acceptor dye | LIFE TECHNOLOGIES CORP (US) | 2012-02-22 | — | — | EP | disclosed |
| US-7169808-B2 | Compounds useful for the preparation of medicaments with phosphodiesterase IV inhibitory activity | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-01-30 | — | — | US | disclosed |
| EP-1441011-A1 | Energy transfer dye containing an aromatic-substituted xanthene dye as donor dye and/or acceptor dye | Applera Corporation (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-1019453-B1 | AROMATIC-SUBSTITUTED XANTHENE DYES | APPLERA CORP (US) | 2004-03-31 | — | — | EP | disclosed |
| US-20030195257-A1 | Compounds useful for the preparation of medicaments with phosphodiesterase IV inhibitory activity | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNTE S.P.A. (IT) | 2003-10-16 | — | — | US | disclosed |
| EP-1292563-A2 | COMPOUNDS USEFUL FOR THE PREPARATION OF MEDICAMENTS WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2003-03-19 | — | — | EP | disclosed |
| WO-2002000593-A2 | COMPOUNDS USEFUL FOR THE PREPARATION OF MEDICAMENTS WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2002-01-03 | — | — | WO | disclosed |
| WO-2002000609-A2 | 2,6,7-SUBSTITUTED TETRALINES USEFUL FOR THE PREPARATION OF MEDICAMENTS WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2002-01-03 | — | — | WO | disclosed |
| EP-1019453-A1 | AROMATIC-SUBSTITUTED XANTHENE DYES | THE PERKIN-ELMER CORPORATION (US) | 2000-07-19 | — | — | EP | disclosed |
| US-6008379-A | USEFUL AS FLUORESCENT DYES FOR LABELING | THE PERKIN-ELMER CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| WO-1999016832-A1 | AROMATIC-SUBSTITUTED XANTHENE DYES | THE PERKIN-ELMER CORPORATION (US) | 1999-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195257-A1 | Compounds useful for the preparation of medicaments with phosphodiesterase IV inhibitory activity | PDE3A, PDE5A, PDE3B | CA2 358/4885CA1 1798/4885TSHR 4452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.