SCHEMBL6326367

SCHEMBL6326367

CCc1c(CC)c(-c2ccccc2)c(C(=O)c2ccccc2)c(-c2ccccc2)c1C(=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
GAA P10253 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
HPGD P15428 5/20 0.42
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
RAB9A P51151 3/20 0.42
LMNA P02545 3/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.40
GRM6 O15303 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
ELANE P08246 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
GCGR P47871 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6328100 0.80 GCGR (0.46) MAPTGAANPSR1HPGDALDH1A1
SCHEMBL6328108 0.79 GCGR (0.45) MAPTGAANPSR1HPGDALDH1A1
SCHEMBL28585328 0.78 AKR1C3 (0.42) MAPTGAANPSR1HPGDALDH1A1
SCHEMBL28203839 0.78 MAPT (0.46) MAPTGAANPSR1HPGDALDH1A1
SCHEMBL27448850 0.76 ALDH1A1 (0.59) MAPTGAANPSR1HPGDALDH1A1
SCHEMBL27514238 0.75 GAA (0.47) MAPTGAANPSR1HPGDALDH1A1
SCHEMBL28552466 0.74 PTGS1 (0.42) MAPTGAANPSR1HPGDALDH1A1
SCHEMBL5587371 0.73 ESR1 (0.42) MAPTGAANPSR1HPGDALDH1A1
SCHEMBL27513901 0.73 GCGR (0.48) MAPTGAANPSR1ALDH1A1CES2
SCHEMBL27711711 0.72 ALDH1A1 (0.45) MAPTGAAHPGDALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100408652-C Photoinitiators and oxygen scanvenging compositions CHEVRON CHEM CO (US) 2008-08-06 CN disclosed
US-6852894-B2 Tribenzoyl compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2005-02-08 US disclosed
EP-0981590-B1 PHOTOINITIATORS AND OXYGEN SCAVENGING COMPOSITIONS CHEVRON PHILLIPS CHEMICAL CO (US) 2004-01-28 EP disclosed
US-20030062505-A1 Tribenzoyl compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP 2003-04-03 US disclosed
US-6139770-A COMPRISES A TRIBENZOYL TRIPHENYLBENZENE OR SUBSTITUTED TRIBENZOYL TRIPHENYLBENZENE PHOTOINITIATOR AND A CATALALYST AS OXYGEN SCAVANGER CHEVRON CHEMICAL COMPANY LLC (US) 2000-10-31 US disclosed
CN-1256707-A Photoinitiator and oxygen scavenging composition CHEVRON CHEM CO (US) 2000-06-14 CN disclosed
EP-0981590-A1 PHOTOINITIATORS AND OXYGEN SCAVENGING COMPOSITIONS Chevron Chemical Company LLC (US) 2000-03-01 EP disclosed
WO-1998051758-A1 PHOTOINITIATORS AND OXYGEN SCAVENGING COMPOSITIONS CHEVRON CHEMICAL COMPANY LLC (US) 1998-11-19 WO disclosed