Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GPR3 | P46089 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412080 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL29374815 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL29518344 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL125196 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL9310670 | 0.73 | KDM4E (0.50) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL4146783 | 0.73 | ALDH1A1 (0.90) | ALDH1A1KDM4EGAAHTTLMNA | |
| Acridone SCHEMBL29641306 | 0.73 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAAHTTLMNA | |
| Acridone SCHEMBL29360611 | 0.73 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL30350396 | 0.73 | ALDH1A1 (0.90) | ALDH1A1KDM4EGAAHTTLMNA | |
| Acridone SCHEMBL11519726 | 0.73 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054650-A1 | Use of glutamate antagonists for the treatment of cancer | IKONOMIDOU HRISSANTHI (DE) | 2005-03-10 | — | — | US | claimed |