Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713630 | 0.68 | ESR1 (0.34) | ESR1THRATHRB | |
| SCHEMBL5713655 | 0.67 | ESR1 (0.36) | ESR1 | |
| SCHEMBL6335483 | 0.67 | CTSD (0.37) | ESR1THRATHRB | |
| SCHEMBL5729135 | 0.66 | ESR1 (0.35) | ESR1 | |
| SCHEMBL5714129 | 0.66 | ESR1 (0.35) | ESR1 | |
| SCHEMBL5714602 | 0.65 | ESR1 (0.34) | ESR1THRATHRB | |
| SCHEMBL5714448 | 0.63 | NOTUM (0.38) | — | |
| SCHEMBL16233041 | 0.63 | AOC3 (0.42) | ESR1 | |
| SCHEMBL8337671 | 0.62 | CHEK1 (0.54) | ESR1 | |
| SCHEMBL6685103 | 0.60 | ESR1 (0.74) | ESR1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050123778-A1 | Polyolefins made by catalyst comprising a noncoordinating anion and articles comprising them | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-06-09 | — | — | US | claimed |
| EP-1406761-A2 | POLYOLEFINS MADE BY CATALYST COMPRISING A NONCOORDINATING ANION AND ARTICLES COMPRISING THEM | ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) | 2004-04-14 | — | — | EP | claimed |
| WO-2003000740-A2 | POLYOLEFINS MADE BY CATALYST COMPRISING A NONCOORDINATING ANION AND ARTICLES COMPRISING THEM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2003-01-03 | — | — | WO | claimed |
| US-20050239790-A1 | Substituted hydroxyethylamine aspartyl protease inhibitors | ELAN PHARMACEUTICALS, INC. | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239790-A1 | Substituted hydroxyethylamine aspartyl protease inhibitors | DNPEP, MME, ANPEP | ESR1 3735/4885THRA 3670/4885THRB 3895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.