Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324484 | 0.90 | KMT2A (0.47) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6322762 | 0.84 | MEN1 (0.48) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6325064 | 0.73 | MAPT (0.55) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6322386 | 0.73 | TRPV1 (0.53) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6323329 | 0.73 | MAPT (0.54) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL24233043 | 0.72 | KMT2A (0.71) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6325807 | 0.71 | TRPV1 (0.51) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6324443 | 0.71 | MAPT (0.54) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6324633 | 0.70 | RAB9A (0.56) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL11148491 | 0.70 | MAPT (0.63) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288290-A1 | Fused heterocyclic kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288290-A1 | Fused heterocyclic kinase inhibitors | MAP3K20, MAP3K19, ABL1 | SMN1; SMN2 3646/4885GAA 1488/4885ALDH1A1 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.