Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330323 | 1.00 | CYP3A4 (0.33) | CYP3A4KDM4E | |
| SCHEMBL6337167 | 0.98 | CYP3A4 (0.36) | CYP3A4KDM4E | |
| SCHEMBL6339242 | 0.90 | CYP3A4 (0.33) | CYP3A4KDM4E | |
| SCHEMBL5595735 | 0.90 | CYP3A4 (0.38) | CYP3A4KDM4E | |
| SCHEMBL6335382 | 0.90 | CYP3A4 (0.38) | CYP3A4KDM4E | |
| SCHEMBL6328203 | 0.90 | CYP3A4 (0.33) | CYP3A4KDM4E | |
| SCHEMBL6326977 | 0.90 | CYP3A4 (0.38) | CYP3A4KDM4E | |
| SCHEMBL6328132 | 0.89 | NR1H2 (0.37) | — | |
| SCHEMBL6504924 | 0.89 | MMP2 (0.38) | CYP3A4KDM4E | |
| SCHEMBL6330260 | 0.89 | CYP3A4 (0.33) | CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953805-B2 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 2005-10-11 | — | — | US | disclosed |
| US-20050170999-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | FILLA SANDRA A (US) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050170999-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | SLC1A2, SLC1A1, SLC1A3 | CYP3A4 3320/4885KDM4E 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.