Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296385 | 0.80 | ALDH1A1 (0.57) | ALDH1A1PTPN1PTPRCKMT2ATDP1 | |
| SCHEMBL27923357 | 0.79 | ALDH1A1 (0.55) | ALDH1A1PTPN1PTPRCKMT2ATDP1 | |
| SCHEMBL543540 | 0.79 | ALDH1A1 (0.55) | ALDH1A1PTPN1PTPRCKMT2ATDP1 | |
| SCHEMBL28269475 | 0.78 | ALDH1A1 (0.55) | ALDH1A1PTPN1PTPRCKMT2ATDP1 | |
| SCHEMBL19695641 | 0.77 | KMT2A (0.54) | ALDH1A1PTPN1PTPRCKMT2ATDP1 | |
| SCHEMBL12128693 | 0.77 | ALDH1A1 (0.58) | ALDH1A1PTPN1PTPRCKMT2ATDP1 | |
| SCHEMBL19105239 | 0.77 | ALDH1A1 (0.58) | ALDH1A1PTPN1PTPRCKMT2ATDP1 | |
| SCHEMBL2859928 | 0.76 | MEN1 (0.54) | KMT2AL3MBTL1MEN1 | |
| SCHEMBL24142683 | 0.76 | KMT2A (0.56) | ALDH1A1PTPN1PTPRCKMT2ATDP1 | |
| SCHEMBL27954863 | 0.76 | PTPN1 (0.57) | ALDH1A1PTPN1PTPRCKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893861-B1 | Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives | LONZA AG (CH) | 2005-05-17 | — | — | US | disclosed |