Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 9/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326006 | 0.84 | PIN1 (1.00) | PIN1LPAR1LPAR3CTSL | |
| SCHEMBL6269412 | 0.81 | PIN1 (0.75) | PIN1LPAR1LPAR3 | |
| SCHEMBL6332054 | 0.80 | PIN1 (0.65) | PIN1ALDH1A1KMT2A | |
| SCHEMBL6269703 | 0.80 | PIN1 (0.72) | PIN1ALDH1A1LPAR1LPAR3CTSL | |
| SCHEMBL6272903 | 0.78 | PIN1 (0.70) | PIN1LPAR1LPAR3CTSL | |
| SCHEMBL6272907 | 0.78 | PIN1 (0.70) | PIN1LPAR1LPAR3CTSL | |
| SCHEMBL6267207 | 0.78 | PIN1 (0.70) | PIN1LPAR1LPAR3 | |
| SCHEMBL6326494 | 0.77 | PIN1 (0.67) | PIN1ALDH1A1LPAR1LPAR3 | |
| SCHEMBL6329760 | 0.77 | PIN1 (1.00) | PIN1LPAR1LPAR3CTSL | |
| SCHEMBL6326344 | 0.77 | PIN1 (1.00) | PIN1LPAR1LPAR3CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PFIZER INC. | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PIN1, PSTPIP2, NIM1K | PIN1 1/4885ALDH1A1 4852/4885LPAR1 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.