⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610687 | 1.00 | HRH3 (0.55) | — | |
| Bromide SCHEMBL31326625 | 0.97 | HRH3 (0.52) | — | |
| Bromide SCHEMBL1846886 | 0.97 | HRH3 (0.52) | — | |
| SCHEMBL989862 | 0.97 | — | — | |
| Bromide SCHEMBL1692850 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL640173 | 0.94 | — | — | |
| SCHEMBL28517081 | 0.90 | — | — | |
| SCHEMBL7911503 | 0.83 | ALOX15 (0.44) | — | |
| SCHEMBL12000706 | 0.83 | — | — | |
| SCHEMBL2099368 | 0.82 | HRH3 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743440-A1 | IONIZABLE LIPIDS | eTheRNA immunotherapies NV (BE) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025016273-A1 | ISOQUINOLINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USES OF ISOQUINOLINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION | 拜西欧斯（北京）生物技术有限公司 | 2025-01-23 | — | — | WO | disclosed |
| WO-2025012376-A1 | IONIZABLE LIPIDS | ETHERNA IMMUNOTHERAPIES NV (BE) | 2025-01-16 | — | — | WO | disclosed |
| US-20240383854-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | HOVIONE FARMACIENCIA SA (PT) | 2024-11-21 | — | — | US | disclosed |
| EP-4392411-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | Hovione Farmaciencia SA (PT) | 2024-07-03 | — | — | EP | disclosed |
| CN-110770214-B | Heterocyclic P2X7 antagonists | 布雷耶疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-3481801-B1 | INDOLINE DERIVATIVES AND METHOD FOR USING AND PRODUCING THE SAME | UNIV ARIZONA (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-3481801-B1 | INDOLINE DERIVATIVES AND METHOD FOR USING AND PRODUCING THE SAME | UNIV ARIZONA (US) | 2023-09-06 | — | — | EP | disclosed |
| US-11685749-B2 | C26-linked rapamycin analogs as mTOR inhibitors | Revolution Medicines, Inc. (US) | 2023-06-27 | — | — | US | disclosed |
| EP-3733663-B1 | 1-[6-[[4-(PHENYLAMINO)-6-QUINAZOLINYL]OXY]-3-AZABICYCLO[3.1.1]HEPT-3-YL]-2-PROPEN-1-ONE DERIVATIVES AND RELATED COMPOUNDS AS IRREVERSIBLE INHIBITORS OF PAN-HER TYROSINE KINASE FOR THE TREATMENT OF CANCER | CHENGDU JINRUI FOUND BIOTECH CO LTD (CN) | 2023-05-17 | — | — | EP | disclosed |
| US-4585869-A | ANTIINFLAMMATORY, ANALGESIC, ANTIULCER | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-04-29 | — | — | US | disclosed |
| US-4549023-A | ANTINFLAMMATORY AGENTS, ANALGESICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-10-22 | — | — | US | disclosed |
| US-4533731-A | ANTIINFLAMMATORY AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0049779-B1 | 3-AMINOINDAZOLE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-31 | — | — | EP | disclosed |
| US-4474964-A | 3-Aminoindazole derivatives | ASAHI, KASEI, KOGYO, KABUSHIKI, KAISHA (JP) | 1984-10-02 | — | — | US | disclosed |
| US-4439380-A | Photopolymerizable composition, especially for dental purposes | ETABLISSEMENT DENTAIRE IVOCLAR (LI) | 1984-03-27 | — | — | US | disclosed |
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |
| EP-0049779-A1 | 3-Aminoindazole derivatives and process for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-04-21 | — | — | EP | disclosed |
| US-4146623-A | SUBSTITUTED FUROIC ACIDS AND ESTERS | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4110351-A | Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts | RICHARDSON-MERRELL INC. (US) | 1978-08-29 | — | — | US | disclosed |