SCHEMBL6329942

SCHEMBL6329942

CC1=CCC(C)(C=CO[SiH2]C(C)(C)C)C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8759250 0.77
SCHEMBL8825024 0.75
SCHEMBL8760395 0.71
SCHEMBL7531545 0.71
SCHEMBL8759132 0.70
SCHEMBL8758690 0.70
SCHEMBL10588633 0.68 HSD11B1 (0.30)
SCHEMBL10642631 0.67
SCHEMBL2835098 0.67 HSD11B1 (0.36)
SCHEMBL3061024 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6889735-B2 Pneumatic tire having a rubber component containing a dendrimer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-05-10 US disclosed
US-20040020576-A1 Pneumatic tire having a rubber component containing a dendrimer THE GOODYEAR TIRE & RUBBER COMPANY 2004-02-05 US disclosed
US-20020068796-A1 Pneumatic tire having a rubber component containing a dendrimer FRANK UWE ERNST (DE) 2002-06-06 US disclosed
EP-1177919-A2 A pneumatic tire having a rubber component containing a dendrimer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-02-06 EP disclosed
US-5276110-A Highly regular multi-arm star polymers NATIONAL RESEARCH COUNCIL OF CANADA (CA) 1994-01-04 US disclosed