Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 5/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6331369 | 1.00 | HTR2C (0.37) | HTR2CHTR2AHTR6EEDPRKCQ | |
| SCHEMBL6331371 | 1.00 | HTR2C (0.37) | HTR2CHTR2AHTR6EEDPRKCQ | |
| Hydrochloric Acid SCHEMBL6332915 | 0.99 | HTR6 (0.36) | HTR2CHTR2AHTR6EEDPRKCQ | |
| Hydrochloric Acid SCHEMBL6332920 | 0.99 | HTR6 (0.36) | HTR2CHTR2AHTR6EEDPRKCQ | |
| Hydrochloric Acid SCHEMBL6332889 | 0.99 | HTR6 (0.36) | HTR2CHTR2AHTR6EEDPRKCQ | |
| Hydrochloric Acid SCHEMBL6332890 | 0.99 | HTR6 (0.36) | HTR2CHTR2AHTR6EEDPRKCQ | |
| Hydrochloric Acid SCHEMBL6332892 | 0.99 | HTR6 (0.36) | HTR2CHTR2AHTR6EEDPRKCQ | |
| Hydrochloric Acid SCHEMBL6333184 | 0.85 | HTR2C (0.35) | HTR2CHTR2AHTR6EEDSLC6A2 | |
| Hydrochloric Acid SCHEMBL6333182 | 0.85 | HTR2C (0.35) | HTR2CHTR2AHTR6EEDSLC6A2 | |
| Hydrochloric Acid SCHEMBL6333185 | 0.85 | HTR2C (0.35) | HTR2CHTR2AHTR6EEDSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881733-B1 | Serotonergic benzofurans | ELI LILLY AND COMPANY (US) | 2005-04-19 | — | — | US | claimed |
| EP-1204659-B1 | SEROTONERGIC BENZOFURANS | LILLY CO ELI (US) | 2003-11-26 | — | — | EP | claimed |
| US-6881733-B1 | Serotonergic benzofurans | ELI LILLY AND COMPANY (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1204659-B1 | SEROTONERGIC BENZOFURANS | LILLY CO ELI (US) | 2003-11-26 | — | — | EP | disclosed |
| EP-1204659-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009122-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |