Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.60 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6331471 | 0.89 | MCHR1 (0.56) | MCHR1KCNH2ACHE | |
| SCHEMBL6333533 | 0.85 | MCHR1 (0.60) | MCHR1KCNH2ACHE | |
| SCHEMBL6329928 | 0.83 | MCHR1 (0.55) | MCHR1KCNH2ACHE | |
| SCHEMBL6337905 | 0.82 | MCHR1 (0.61) | MCHR1KCNH2ACHEHTR4 | |
| SCHEMBL6338073 | 0.80 | MCHR1 (0.59) | MCHR1KCNH2ACHE | |
| SCHEMBL6329320 | 0.80 | MCHR1 (0.67) | MCHR1KCNH2 | |
| SCHEMBL6332263 | 0.80 | MCHR1 (0.57) | MCHR1KCNH2ACHEHTR4 | |
| Hydrochloric Acid SCHEMBL6333738 | 0.79 | MCHR1 (0.66) | MCHR1KCNH2 | |
| SCHEMBL6329342 | 0.76 | KDM4E (0.58) | MCHR1KCNH2ACHE | |
| SCHEMBL6333496 | 0.76 | MCHR1 (0.91) | MCHR1KCNH2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABOTT LABORATORIES | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | MCHR1 1/4885KCNH2 1620/4885ACHE 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.