Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017506 | 0.83 | TSHR (0.64) | TSHRMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL27352994 | 0.83 | TSHR (0.59) | TSHRMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL5158714 | 0.83 | TSHR (0.59) | TSHRMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL5197853 | 0.83 | TSHR (0.59) | TSHRMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL28983039 | 0.79 | TSHR (0.55) | TSHRMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL5197224 | 0.79 | TSHR (0.55) | TSHRMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL5194626 | 0.79 | TSHR (0.55) | TSHRMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8187567 | 0.79 | ALDH1A1 (0.55) | TSHRMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1606582 | 0.79 | TSHR (0.65) | TSHRMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL5313340 | 0.79 | TSHR (0.72) | TSHRMAPTHPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047166-A1 | METHOD FOR SYNTHESIZING TRANYLCYPROMINE INTERMEDIATE | 凯特立斯（深圳）科技有限公司 | 2021-03-18 | — | — | WO | disclosed |
| CN-110627628-A | Beta-iodo-difluoropropanone derivative and preparation method thereof | 上海应用技术大学 | 2019-12-31 | — | — | CN | disclosed |
| EP-2419400-A1 | MONOAMINE REUPTAKE INHIBITORS | RESEARCH TRIANGLE INSTITUTE (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-1401819-A1 | 5-HT RECEPTOR LIGANDS AND USES THEREOF | Pfizer Products Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003000663-A1 | 5-HT RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |