Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332833 | 1.00 | EED (0.33) | EEDPRKCQHTR2AHTR2CHTR1A | |
| SCHEMBL6332836 | 1.00 | EED (0.33) | EEDPRKCQHTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL6333080 | 0.99 | EED (0.33) | EEDPRKCQHTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL6333078 | 0.99 | EED (0.33) | EEDPRKCQHTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL6333083 | 0.99 | EED (0.33) | EEDPRKCQHTR2AHTR2CHTR1A | |
| SCHEMBL6334206 | 0.84 | EED (0.37) | EEDPRKCQHTR2AHTR2CHTR1A | |
| SCHEMBL6334203 | 0.84 | EED (0.37) | EEDPRKCQHTR2AHTR2CHTR1A | |
| SCHEMBL6334205 | 0.84 | EED (0.37) | EEDPRKCQHTR2AHTR2CHTR1A | |
| SCHEMBL6331237 | 0.83 | HTR2C (0.37) | EEDPRKCQHTR2AHTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL6333196 | 0.83 | EED (0.36) | EEDPRKCQHTR2AHTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881733-B1 | Serotonergic benzofurans | ELI LILLY AND COMPANY (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1204659-B1 | SEROTONERGIC BENZOFURANS | LILLY CO ELI (US) | 2003-11-26 | — | — | EP | disclosed |
| EP-1204659-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009122-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |