Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634407 | 0.87 | CCR2 (0.62) | CCR2KCNH2 | |
| SCHEMBL633423 | 0.86 | CCR2 (0.48) | CCR2KCNH2 | |
| SCHEMBL647707 | 0.86 | CCR2 (0.60) | CCR2KCNH2 | |
| SCHEMBL627764 | 0.85 | CCR2 (0.66) | CCR2KCNH2 | |
| SCHEMBL633159 | 0.85 | CCR2 (0.53) | CCR2KCNH2 | |
| SCHEMBL3719908 | 0.85 | CCR2 (0.61) | CCR2KCNH2 | |
| SCHEMBL634402 | 0.84 | CCR2 (0.52) | CCR2KCNH2 | |
| SCHEMBL633308 | 0.84 | CCR2 (0.53) | CCR2KCNH2 | |
| SCHEMBL634029 | 0.84 | CCR2 (0.52) | CCR2KCNH2 | |
| SCHEMBL633314 | 0.84 | CCR2 (0.51) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419419-A1 | 4-AZETIDINYL-1-PHENYL-CYCLOHEXANE ANTAGONISTS OF CCR2 | Janssen Pharmaceutica, N.V. (BE) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010121046-A1 | 4-AZETIDINYL-1-PHENYL-CYCLOHEXANE ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-21 | — | — | WO | disclosed |