SCHEMBL6333307

SCHEMBL6333307

Nc1cccc(Oc2cccc(CC(F)C(F)(F)C(F)(F)F)c2)c1N

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TAAR1 Q96RJ0 2/20 0.35
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CETP P11597 7/20 0.33
RCE1 Q9Y256 1/20 0.33
FDFT1 P37268 2/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
MPO P05164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6325557 0.87 ESR1 (0.33) GAAALDH1A1MAPTL3MBTL1RCE1
SCHEMBL6333303 0.80 GAA (0.37) GAAALDH1A1MAPTNPSR1L3MBTL1
SCHEMBL6323002 0.79 TAAR1 (0.46) GAAALDH1A1TAAR1L3MBTL1CETP
SCHEMBL6331625 0.74 ALDH1A1 (0.45) GAAALDH1A1TAAR1MAPTL3MBTL1
SCHEMBL6141193 0.72 ALDH1A1 (0.56) GAAALDH1A1MAPTNPSR1L3MBTL1
SCHEMBL6330909 0.72 ALDH1A1 (0.43) GAAALDH1A1MAPTL3MBTL1RCE1
SCHEMBL6322998 0.69 ALDH1A1 (0.44) GAAALDH1A1TAAR1
SCHEMBL6325554 0.69 GAA (0.31) GAAALDH1A1MAPTL3MBTL1CETP
SCHEMBL29137112 0.68 GAA (0.39) GAAALDH1A1MAPTNPSR1L3MBTL1
SCHEMBL4529192 0.68 GAA (0.49) GAAALDH1A1MAPTNPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050272608-A1 Polyimide metal laminate and its production method MITSUI CHEMICALS, INC. (JP) 2005-12-08 US disclosed