⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29422918 | 0.72 | LMNA (0.44) | — | |
| SCHEMBL42913 | 0.69 | — | — | |
| SCHEMBL7744397 | 0.69 | — | — | |
| SCHEMBL6971277 | 0.67 | — | — | |
| SCHEMBL130233 | 0.67 | — | — | |
| SCHEMBL7158013 | 0.67 | — | — | |
| SCHEMBL100367 | 0.67 | — | — | |
| SCHEMBL5604583 | 0.67 | — | — | |
| SCHEMBL17476091 | 0.65 | — | — | |
| SCHEMBL9412208 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064290-B1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-09 | — | — | EP | claimed |
| US-20090054597-A1 | Metathesis of Nitrile Rubbers In the Presence of Transition Metal Complex Catalysts | LANXESS DEUTSCHLAND GMBH (DE) | 2009-02-26 | — | — | US | claimed |
| US-7034156-B2 | Method for the production of 1-amino-3-phenyluracil derivatives | BAYER CROPSCIENCE AG (DE) | 2006-04-25 | — | — | US | claimed |
| US-20040147400-A1 | Method for the production of 1-amino-3-phenyl- uracil derivatives | BAYER CROPSCIENCE AG (DE) | 2004-07-29 | — | — | US | claimed |
| US-6225334-B1 | AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-01 | — | — | US | claimed |
| US-12024519-B2 | Fused ring derivative having MGAT-2 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2024-07-02 | — | — | US | disclosed |
| CN-113501821-B | Fused ring derivatives having MGAT-2 inhibitory activity | 盐野义制药株式会社 | 2024-04-09 | — | — | CN | disclosed |
| US-20220135577-A1 | DIHYDROPYRAZOLOPYRAZINONE DERIVATIVE HAVING MGAT2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2022-05-05 | — | — | US | disclosed |
| US-20220073518-A1 | FUSED RING DERIVATIVE HAVING MGAT-2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2022-03-10 | — | — | US | disclosed |
| US-11198695-B2 | Fused ring derivative having MGAT-2 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2021-12-14 | — | — | US | disclosed |
| EP-3909583-A1 | DIHYDROPYRAZOLOPYRAZINONE DERIVATIVE HAVING MGAT2 INHIBITORY ACTIVITY | Shionogi & Co., Ltd (JP) | 2021-11-17 | — | — | EP | disclosed |
| US-20200291025-A1 | FUSED RING DERIVATIVE HAVING MGAT-2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2020-09-17 | — | — | US | disclosed |
| US-8129355-B2 | Nuclear receptor-based inducible gene expression system; modulating the expression of a gene in a host cell by introducing into the host cell a gene expression modulation system and activating that system using 5-ethyl-2,3-dihydro-benzo[1,4]dioxine-6-carboxylic acid (1-benzoyl-cyclopentyl)-amide | INTREXON CORPORATION (US) | 2012-03-06 | — | — | US | disclosed |
| US-20080125465-A1 | Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORPORATION (US) | 2008-05-29 | — | — | US | disclosed |
| US-7034156-B2 | Method for the production of 1-amino-3-phenyluracil derivatives | BAYER CROPSCIENCE AG (DE) | 2006-04-25 | — | — | US | disclosed |
| US-20040147400-A1 | Method for the production of 1-amino-3-phenyl- uracil derivatives | BAYER CROPSCIENCE AG (DE) | 2004-07-29 | — | — | US | disclosed |
| US-6054621-A | FOR CONTROLLING PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-25 | — | — | US | disclosed |
| EP-0991626-A2 | PYRIMIDIN-2,4,6-TRION DERIVATIVES, METHOD FOR PRODUCING THE SAME AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 2000-04-12 | — | — | EP | disclosed |
| EP-0772587-B1 | N-ALKOXY-AMIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998058915-A2 | PYRIMIDIN-2,4,6-TRION DERIVATIVES AND THEIR USE AS METALLOPROTEASE-INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 1998-12-30 | — | — | WO | disclosed |