Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATF4 | P18848 | 6/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6331382 | 0.83 | MCHR1 (0.52) | MCHR1KCNH2RXFP1MAPTTP53 | |
| SCHEMBL6331249 | 0.81 | MCHR1 (0.55) | MCHR1KCNH2MAPTACHE | |
| Hydrochloric Acid SCHEMBL6333740 | 0.80 | MCHR1 (0.54) | MCHR1KCNH2MAPTACHE | |
| SCHEMBL6332065 | 0.76 | ALDH1A1 (0.59) | MCHR1KCNH2ALDH1A1 | |
| SCHEMBL6333533 | 0.73 | MCHR1 (0.60) | MCHR1KCNH2ACHE | |
| SCHEMBL6331018 | 0.70 | ALDH1A1 (0.59) | MCHR1KCNH2ALDH1A1 | |
| SCHEMBL6337862 | 0.69 | MCHR1 (0.66) | MCHR1KCNH2ACHE | |
| SCHEMBL22617345 | 0.68 | MAOB (0.65) | MCHR1KCNH2KMT2AMEN1 | |
| SCHEMBL6333396 | 0.67 | MCHR1 (0.63) | MCHR1KCNH2ACHE | |
| SCHEMBL6333857 | 0.66 | MCHR1 (0.54) | MCHR1KCNH2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABOTT LABORATORIES | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | MCHR1 1/4885KCNH2 1620/4885RXFP1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.