⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28156558 | 0.86 | TSHR (0.32) | — | |
| SCHEMBL8691854 | 0.82 | — | — | |
| SCHEMBL29093054 | 0.79 | TSHR (0.47) | — | |
| SCHEMBL29093233 | 0.79 | TSHR (0.47) | — | |
| SCHEMBL3885660 | 0.79 | TSHR (0.47) | — | |
| SCHEMBL27800 | 0.79 | — | — | |
| SCHEMBL619867 | 0.79 | TSHR (0.47) | — | |
| SCHEMBL428320 | 0.79 | TSHR (0.47) | — | |
| SCHEMBL6809036 | 0.79 | — | — | |
| SCHEMBL28142524 | 0.78 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900243-B2 | Phenylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2005-05-31 | — | — | US | disclosed |
| CN-1149214-C | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| EP-1263715-B1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-04-28 | — | — | EP | disclosed |
| US-20030065174-A1 | Novel phenylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2003-04-03 | — | — | US | disclosed |
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-6041157-A | Environmentally sensitive compositions of matter based on 3H-fluoren-3-ylidenes and process for making same | GOETZ FREDERICK JAMES (US) | 2000-03-21 | — | — | US | disclosed |
| US-6022822-A | Organotin compound and catalyst for transesterification comprising the same | RYOJI NOYORI (JP) | 2000-02-08 | — | — | US | disclosed |
| US-4855322-A | ANTIANDROGENS;SKIN DISORDERS | CBD CORPORATION (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0293146-A1 | Benzofuro [3,2-c] quinoline compounds | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-11-30 | — | — | EP | disclosed |
| US-4731458-A | Spiro[bicyclo[3.2.0]heptane-6,2'-oxirane] derivatives | CBD CORPORATION (US) | 1988-03-15 | — | — | US | disclosed |
| US-4689349-A | Anti-tumor halo bicyclo alkanones | CBD CORPORATION (US) | 1987-08-25 | — | — | US | disclosed |
| US-4689345-A | ANTIANDROGENS | CBD CORPORATION (US) | 1987-08-25 | — | — | US | disclosed |
| US-4040977-A | HALOACETAMIDE OR THIOCYANOACETAMIDE-ALCOHOL-FORMALDEHYDE CONDENSATES | STERLING DRUG INC. (US) | 1977-08-09 | — | — | US | disclosed |