Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.53 |
| ▸ | DHFR | P00374 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514711 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2CACNA1CDHFRALDH1A1KDM4E | |
| SCHEMBL6338671 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2CACNA1CDHFRALDH1A1KDM4E | |
| SCHEMBL6346211 | 0.82 | CACNA1B (0.49) | CACNA1BHTT | |
| SCHEMBL7412174 | 0.81 | CACNA1C (0.79) | SMN1; SMN2CACNA1CALDH1A1CACNA1B | |
| SCHEMBL7522407 | 0.81 | CACNA1C (0.39) | SMN1; SMN2CACNA1CDHFRCACNA1BHTT | |
| SCHEMBL6338254 | 0.81 | CACNA1B (0.45) | ALDH1A1CACNA1BHTTSLC9A1 | |
| SCHEMBL6340945 | 0.81 | CACNA1F (0.53) | CACNA1CCACNA1BHTT | |
| SCHEMBL9475129 | 0.79 | DHFR (0.45) | SMN1; SMN2CACNA1CDHFRALDH1A1KDM4E | |
| SCHEMBL10670179 | 0.78 | CACNA1C (0.47) | SMN1; SMN2CACNA1CDHFRALDH1A1KDM4E | |
| SCHEMBL6338479 | 0.75 | CACNA1B (0.43) | CACNA1BHTTSLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855716-B2 | Dihydropyrimidine compounds and compositions containing the same | AJINOMOTO CO., INC. (JP) | 2005-02-15 | — | — | US | disclosed |