Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329797 | 0.87 | NR4A2 (0.40) | NR4A2KCNH2HTR4HTR3ADRD2 | |
| SCHEMBL6326529 | 0.87 | NR4A2 (0.40) | NR4A2KCNH2HTR4HTR3ADRD2 | |
| SCHEMBL6326744 | 0.86 | NR4A2 (0.37) | NR4A2KCNH2HTR4 | |
| SCHEMBL6329808 | 0.82 | HTR4 (0.41) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL6326663 | 0.81 | HTR4 (0.40) | NR4A2KCNH2HTR4HTR3ADRD2 | |
| SCHEMBL6328215 | 0.80 | NR4A2 (0.46) | NR4A2KCNH2HTR4DRD2DRD4 | |
| SCHEMBL6329782 | 0.80 | NR4A2 (0.41) | NR4A2KCNH2HTR4 | |
| SCHEMBL14258189 | 0.80 | NR4A2 (0.53) | NR4A2HTR4 | |
| SCHEMBL6328985 | 0.79 | HTR4 (0.41) | KCNH2HTR4HTR3ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6326593 | 0.79 | NR4A2 (0.52) | NR4A2HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979690-B2 | Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators | PFIZER INC. (US) | 2005-12-27 | — | — | US | disclosed |