Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL6337593 | 0.86 | MEN1 (0.41) | MEN1KMT2ACACNA1BADRA1DADRA1A | |
| SCHEMBL6340776 | 0.83 | CACNA1F (0.53) | MEN1KMT2AMAPK1CACNA1BADRA1D | |
| SCHEMBL7512719 | 0.83 | MAPK1 (0.40) | MEN1KMT2AMAPK1CACNA1BADRA1D | |
| SCHEMBL6339432 | 0.82 | CACNA1B (0.47) | MEN1KMT2ACACNA1BADRA1DADRA1A | |
| SCHEMBL6340733 | 0.80 | ADRA1D (0.51) | MAPK1CACNA1BADRA1DADRA1AADRA1B | |
| SCHEMBL6337715 | 0.78 | CACNA1B (0.67) | MEN1KMT2ACACNA1BADRA1DADRA1A | |
| SCHEMBL6337712 | 0.78 | CACNA1B (0.67) | MEN1KMT2ACACNA1BADRA1DADRA1A | |
| SCHEMBL6338019 | 0.75 | ADRA1D (0.55) | CACNA1BADRA1DADRA1AADRA1BCACNA1F | |
| SCHEMBL28744261 | 0.75 | CACNA1B (0.59) | CACNA1BADRA1DADRA1AADRA1B | |
| SCHEMBL7659273 | 0.71 | CACNA1B (0.68) | MEN1KMT2ACACNA1BRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855716-B2 | Dihydropyrimidine compounds and compositions containing the same | AJINOMOTO CO., INC. (JP) | 2005-02-15 | — | — | US | disclosed |
| EP-1193259-A1 | DIHYDROPYRIMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2002-04-03 | — | — | EP | disclosed |