Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 12/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223355 | 0.83 | ALDH1A1 (0.41) | KDM4EGBA1LMNAALDH1A1POLB | |
| SCHEMBL1383369 | 0.83 | ALDH1A1 (0.41) | KDM4EGBA1LMNAALDH1A1POLB | |
| SCHEMBL6219896 | 0.83 | ALDH1A1 (0.41) | KDM4EGBA1LMNAALDH1A1POLB | |
| SCHEMBL4820832 | 0.81 | KDR (0.55) | FLT1KDM4EHSD17B10POLB | |
| SCHEMBL14267794 | 0.73 | FLT1 (0.65) | FLT1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL12384586 | 0.72 | ALDH1A1 (0.68) | KDM4ELMNAALDH1A1MAPTPKM | |
| SCHEMBL6612202 | 0.70 | FLT1 (0.63) | FLT1KDM4EHSD17B10 | |
| SCHEMBL6223769 | 0.69 | GBA1 (0.53) | GBA1LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL1386115 | 0.69 | GBA1 (0.53) | GBA1LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL6223107 | 0.69 | GBA1 (0.53) | GBA1LMNAPOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911440-B2 | Phthalazine derivatives for treating inflammatory diseases | NOVARTIS AG (CH) | 2005-06-28 | — | — | US | disclosed |