SCHEMBL633827

SCHEMBL633827

C=Cc1ccccc1C.C=Cc1ccccc1CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
TSHR P16473 2/20 0.47
CDK4 P11802 1/20 0.37
CCND1 P24385 1/20 0.37
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
ACHE P22303 2/20 0.35
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
MAPT P10636 1/20 0.34
SHBG P04278 1/20 0.34
KMT2A Q03164 2/20 0.33
PTGER1 P34995 1/20 0.33
PTGER4 P35408 1/20 0.33
PTGER3 P43115 1/20 0.33
PTGER2 P43116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14959 0.90 ALDH1A1 (0.44) ALDH1A1TSHRGABRA1GABRB2MAPT
SCHEMBL29749448 0.90 ALDH1A1 (0.44) ALDH1A1TSHRGABRA1GABRB2MAPT
SCHEMBL9576114 0.88 ALDH1A1 (0.43) ALDH1A1TSHRGABRA1GABRB2MAPT
Water SCHEMBL28085262 0.88 ALDH1A1 (0.43) ALDH1A1TSHRGABRA1GABRB2MAPT
Benzene SCHEMBL9141668 0.88 ALDH1A1 (0.43) ALDH1A1TSHRGABRA1GABRB2MAPT
SCHEMBL6849255 0.88 ALDH1A1 (0.43) ALDH1A1TSHRGABRA1GABRB2MAPT
SCHEMBL28802097 0.88 ALDH1A1 (0.43) ALDH1A1TSHRGABRA1GABRB2MAPT
O-Xylene SCHEMBL28827781 0.87 ALDH1A1 (0.38) ALDH1A1TSHRCDK4CCND1TAAR1
SCHEMBL28095012 0.87 ALDH1A1 (0.38) ALDH1A1TSHRCDK4CCND1TAAR1
Methylamine SCHEMBL1256495 0.86 ALDH1A1 (0.41) ALDH1A1TSHRGABRA1GABRB2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399703-B1 Method for the continuous production of thermoplastic molding materials BASF AKTIENGESELLSCHAFT (DE) 2002-06-04 US claimed
CN-117222694-A Rheology modified olefin-based polymer compositions and methods of making the same 陶氏环球技术有限责任公司 2023-12-12 CN disclosed
EP-2181126-B1 METHOD FOR PROCESSING EFFLUENT FROM CHLOROMETHYLATION OF VINYL AROMATIC POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-02-22 EP disclosed